BDBM50582807 CHEMBL5076307

SMILES [H][C@@]12CN(C[C@@]1([H])OCCN2)c1cnc2c(COC22CN(C[C@H]3CN(C[C@@H](C)O3)c3ccc(C#N)c4nc([2H])ccc34)C2)c1

InChI Key InChIKey=RBFYADJEFGNDEK-PVROUYRZSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50582807   

TargetToll-like receptor 7(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50582807(CHEMBL5076307)
Affinity DataIC50:  4nMAssay Description:Inhibition of human TLR7 expressed in HEK-Blue hTLR7 cells assessed as inhibition of TLR7 by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 9(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50582807(CHEMBL5076307)
Affinity DataIC50:  39nMAssay Description:Inhibition of human TLR9 expressed in HEK-Blue hTLR9 cells assessed as inhibition of TLR9 by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 8(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50582807(CHEMBL5076307)
Affinity DataIC50:  10nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue hTLR8 cells assessed as inhibition of TLR8 by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed