BDBM50585044 CHEMBL5088392

SMILES [H][C@@]12[C@@H](C)OC(=O)[C@@]11CN(C[C@H]1[C@H](C)[C@@H](C)[C@@H]2\C=C\c1ccc(cn1)-c1ccccc1C#N)C(=O)NCC

InChI Key InChIKey=UAELFEWPCXTKFL-IDKUMADTSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50585044   

TargetProteinase-activated receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50585044(CHEMBL5088392)
Affinity DataIC50:  7nMAssay Description:Antagonist activity at human PAR-1 expressed in HEK293 cells assessed as reduction in TRAP induced calcium signal at 3 uM by FLIPR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50585044(CHEMBL5088392)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of [35S]MK-499 binding to hERG expressed in HEK293 cells at 60 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50585044(CHEMBL5088392)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of [35S]MK-499 binding to hERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed