BDBM50585276 CHEMBL5093130

SMILES CC(C)(C(O)=O)c1nn(Cc2cn3cc(OCC4CC4)c(Cl)cc3n2)c2ccccc2c1=O

InChI Key InChIKey=QMYJFAKBJFCKDD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50585276   

TargetSphingosine 1-phosphate receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50585276(CHEMBL5093130)
Affinity DataIC50:  7.70nMAssay Description:Antagonist activity at human S1P2 receptor expressed in CHO cells assessed as inhibition of calcium fluxMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50585276(CHEMBL5093130)
Affinity DataIC50:  361nMAssay Description:Antagonist activity at human S1P2 in HFL1 cells assessed as inhibition of EC80 S1P-induced IL8 release incubated for 16 to 24 hrs in presence of 2% H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50585276(CHEMBL5093130)
Affinity DataIC50:  21nMAssay Description:Antagonist activity at human S1P2 in HFL1 cells assessed as inhibition of EC80 S1P-induced IL8 release incubated for 16 to 24 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50585276(CHEMBL5093130)
Affinity DataIC50:  105nMAssay Description:Antagonist activity at human S1P2 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed