BDBM50585511 CHEMBL5077126

SMILES CCc1cc(O)c(F)cc1-c1cc(NC2CCN(C)CC2)c2nc(N)ncc2c1

InChI Key InChIKey=USBPOYIQCXNWQH-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50585511   

TargetJAK3/JAK1(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50585511(CHEMBL5077126)
Affinity DataIC50:  25nMAssay Description:Inhibition of JAK1/JAK3 signalling in human PBMC assessed as inhibition of IL-2 stimulated IFN-gamma release incubated for 1 hr followed by IL-2 stim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed