BDBM50587876 CHEMBL5208108
SMILES [H][C@]12CN(C[C@@H](C)N1Cc1cc(ccc21)N1CC2CNCC2(C1)OC)c1ccc(C#N)c2ncccc12
InChI Key InChIKey=STWJRRQLEOCSIF-LJWPGGNMSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50587876
Affinity DataIC50: <3nMAssay Description:Antagonist activity at R848 stimulated TRL7 in HEK-Blue hTLR7 cells assessed as inhibition of NF kappa B/Ap-1 activation measured after 20 hrs by SEA...More data for this Ligand-Target Pair
Affinity DataIC50: <32nMAssay Description:Antagonist activity at R848 stimulated TRL9 in HEK-Blue hTLR9 cells assessed as inhibition of NF kappa B/Ap-1 activation measured after 20 hrs by SEA...More data for this Ligand-Target Pair
Affinity DataIC50: <3nMAssay Description:Antagonist activity at R848 stimulated TRL8 in HEK-Blue hTLR8 cells assessed as inhibition of NF kappa B/Ap-1 activation measured after 20 hrs by SEA...More data for this Ligand-Target Pair