BDBM50589443 CHEMBL5193820

SMILES Cc1cc(N)c(cc1C(=O)Nc1cc(F)c(F)c(F)c1)S(N)(=O)=O

InChI Key InChIKey=RLCJNRRDMJQHSR-UHFFFAOYSA-N

Data  4 IC50  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50589443   

TargetCapsid protein(Hepatitis B virus)
Promidis

Curated by ChEMBL
LigandPNGBDBM50589443(CHEMBL5193820)
Affinity DataEC50:  62nMAssay Description:Modulation of capsid assembly in HBV infected in human HePAD38 cells assessed as inhibition of viral DNA replication measured after 96 hrs by qPCR an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCapsid protein(Hepatitis B virus)
Promidis

Curated by ChEMBL
LigandPNGBDBM50589443(CHEMBL5193820)
Affinity DataEC50:  60nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replicationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCapsid protein(Hepatitis B virus)
Promidis

Curated by ChEMBL
LigandPNGBDBM50589443(CHEMBL5193820)
Affinity DataEC50:  1.05E+3nMAssay Description:Modulation of capsid assembly in HBV infected in human HePAD38 cells assessed as inhibition of viral DNA replication in presence of 40% normal human ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCapsid protein(Hepatitis B virus)
Promidis

Curated by ChEMBL
LigandPNGBDBM50589443(CHEMBL5193820)
Affinity DataEC50:  28nMAssay Description:Modulation of capsid assembly in HBV genotype A infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replicationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCapsid protein(Hepatitis B virus)
Promidis

Curated by ChEMBL
LigandPNGBDBM50589443(CHEMBL5193820)
Affinity DataEC50:  28nMAssay Description:Modulation of capsid assembly in HBV genotype B infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replicationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Promidis

Curated by ChEMBL
LigandPNGBDBM50589443(CHEMBL5193820)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCapsid protein(Hepatitis B virus)
Promidis

Curated by ChEMBL
LigandPNGBDBM50589443(CHEMBL5193820)
Affinity DataEC50:  39nMAssay Description:Modulation of capsid assembly in HBV genotype D infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replicationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCapsid protein(Hepatitis B virus)
Promidis

Curated by ChEMBL
LigandPNGBDBM50589443(CHEMBL5193820)
Affinity DataEC50:  28nMAssay Description:Modulation of capsid assembly in HBV genotype E infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replicationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Promidis

Curated by ChEMBL
LigandPNGBDBM50589443(CHEMBL5193820)
Affinity DataIC50:  1.24E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Promidis

Curated by ChEMBL
LigandPNGBDBM50589443(CHEMBL5193820)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Promidis

Curated by ChEMBL
LigandPNGBDBM50589443(CHEMBL5193820)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCapsid protein(Hepatitis B virus)
Promidis

Curated by ChEMBL
LigandPNGBDBM50589443(CHEMBL5193820)
Affinity DataEC50:  28nMAssay Description:Modulation of capsid assembly in HBV genotype C infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replicationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed