BDBM50589443 CHEMBL5193820
SMILES Cc1cc(N)c(cc1C(=O)Nc1cc(F)c(F)c(F)c1)S(N)(=O)=O
InChI Key InChIKey=RLCJNRRDMJQHSR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50589443
Affinity DataEC50: 62nMAssay Description:Modulation of capsid assembly in HBV infected in human HePAD38 cells assessed as inhibition of viral DNA replication measured after 96 hrs by qPCR an...More data for this Ligand-Target Pair
Affinity DataEC50: 60nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replicationMore data for this Ligand-Target Pair
Affinity DataEC50: 1.05E+3nMAssay Description:Modulation of capsid assembly in HBV infected in human HePAD38 cells assessed as inhibition of viral DNA replication in presence of 40% normal human ...More data for this Ligand-Target Pair
Affinity DataEC50: 28nMAssay Description:Modulation of capsid assembly in HBV genotype A infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replicationMore data for this Ligand-Target Pair
Affinity DataEC50: 28nMAssay Description:Modulation of capsid assembly in HBV genotype B infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replicationMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Promidis
Curated by ChEMBL
Promidis
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair
Affinity DataEC50: 39nMAssay Description:Modulation of capsid assembly in HBV genotype D infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replicationMore data for this Ligand-Target Pair
Affinity DataEC50: 28nMAssay Description:Modulation of capsid assembly in HBV genotype E infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replicationMore data for this Ligand-Target Pair
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 28nMAssay Description:Modulation of capsid assembly in HBV genotype C infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replicationMore data for this Ligand-Target Pair