BDBM50589693 CHEMBL5177523

SMILES COC(C)(C)C(=O)NC(=O)Nc1ccc(Oc2ccnc(c2)-c2cnc(C)s2)c(C)n1

InChI Key InChIKey=JGHJSVPEMJVPKE-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50589693   

TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589693(CHEMBL5177523)
Affinity DataIC50:  9.10nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589693(CHEMBL5177523)
Affinity DataIC50: >3.30E+3nMAssay Description:Inhibition of His-tagged recombinant human FLT3 (564 to 958 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589693(CHEMBL5177523)
Affinity DataIC50: >3.30E+3nMAssay Description:Inhibition of N-terminal His-Glu-TEV-tagged MET (unknown origin) (1050 to 1360 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589693(CHEMBL5177523)
Affinity DataIC50: >3.30E+3nMAssay Description:Inhibition of N-terminal GST-tagged PDGFRbeta (unknown origin) (557 to 1106 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589693(CHEMBL5177523)
Affinity DataIC50: >3.30E+3nMAssay Description:Inhibition of VEGFR2 (unknown origin) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589693(CHEMBL5177523)
Affinity DataIC50:  700nMAssay Description:Inhibition of N-terminal GST-tagged PDGFRalpha (unknown origin) (550 to 1089 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed