BDBM50589693 CHEMBL5177523
SMILES COC(C)(C)C(=O)NC(=O)Nc1ccc(Oc2ccnc(c2)-c2cnc(C)s2)c(C)n1
InChI Key InChIKey=JGHJSVPEMJVPKE-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50589693
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals
Curated by ChEMBL
Deciphera Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 9.10nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Deciphera Pharmaceuticals
Curated by ChEMBL
Deciphera Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >3.30E+3nMAssay Description:Inhibition of His-tagged recombinant human FLT3 (564 to 958 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals
Curated by ChEMBL
Deciphera Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >3.30E+3nMAssay Description:Inhibition of N-terminal His-Glu-TEV-tagged MET (unknown origin) (1050 to 1360 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Deciphera Pharmaceuticals
Curated by ChEMBL
Deciphera Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >3.30E+3nMAssay Description:Inhibition of N-terminal GST-tagged PDGFRbeta (unknown origin) (557 to 1106 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Deciphera Pharmaceuticals
Curated by ChEMBL
Deciphera Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >3.30E+3nMAssay Description:Inhibition of VEGFR2 (unknown origin) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Deciphera Pharmaceuticals
Curated by ChEMBL
Deciphera Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of N-terminal GST-tagged PDGFRalpha (unknown origin) (550 to 1089 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair