BDBM50593147 CHEMBL5203777

SMILES Cc1cccc2sc(NC(=O)CCN3CCN(CC3)C3CCCCC3)nc12

InChI Key InChIKey=VHQXTKHIQIUABO-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50593147   

TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Yeditepe University

Curated by ChEMBL
LigandPNGBDBM50593147(CHEMBL5203777)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Yeditepe University

Curated by ChEMBL
LigandPNGBDBM50593147(CHEMBL5203777)
Affinity DataKi:  213nMAssay Description:Displacement of [3H]ifenprodil from recombinant human GluN2B NMDA receptor (unknown origin) expressed in dexamethasone-induced mouse L-M(TK-) cell af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Yeditepe University

Curated by ChEMBL
LigandPNGBDBM50593147(CHEMBL5203777)
Affinity DataKi:  233nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Yeditepe University

Curated by ChEMBL
LigandPNGBDBM50593147(CHEMBL5203777)
Affinity DataIC50:  1.09E+4nMAssay Description:Inhibition of human recombinant AChe using acetylthiocholine iodide as substrate incubated for 10 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCholinesterase(Homo sapiens (Human))
Yeditepe University

Curated by ChEMBL
LigandPNGBDBM50593147(CHEMBL5203777)
Affinity DataIC50:  3.19E+3nMAssay Description:Inhibition of human recombinant BuChe using butyrylthiocholine iodide as substrate incubated for 10 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed