BDBM50595508 CHEMBL5183377
SMILES COc1ccc(-c2cn3ccc(cc3n2)N2CCN(CC2)C(C)C)c(OC)c1
InChI Key InChIKey=UIQKQMIPZIGLSU-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50595508
TargetToll-like receptor 9(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Antagonist activity at human TLR9 expressed in HEK-blue hTLR9 cells assessed as inhibition of CpGB-induced NFkappaB activation preincubated with comp...More data for this Ligand-Target Pair
TargetToll-like receptor 8(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 8.32E+3nMAssay Description:Antagonist activity at human TLR8 expressed in HEK-blue hTLR8 cells assessed as inhibition of CL075-induced NFkappaB activation preincubated with com...More data for this Ligand-Target Pair
TargetToll-like receptor 9(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Antagonist activity at TLR9 in human pDCs inhibition of CpGB-induced NFkappaB activation by measuring IFN-alpha levels preincubated with compound for...More data for this Ligand-Target Pair
TargetToll-like receptor 7(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 466nMAssay Description:Antagonist activity at human TLR7 expressed in HEK-blue hTLR7 cells assessed as inhibition of CL264-induced NFkappaB activation preincubated with com...More data for this Ligand-Target Pair