BDBM50596624 CHEMBL5204261

SMILES CC(C)c1ccc(NC(=S)NC(=O)C23CC4CC(CC(C4)C2)C3)c(Br)c1

InChI Key InChIKey=PRBMAGHYRALAOF-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50596624   

TargetP2X purinoceptor 4(Homo sapiens (Human))
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50596624(CHEMBL5204261)
Affinity DataEC50:  1.01E+4nMAssay Description:Negative allosteric modulation activity at human P2X4 receptor expressed in human 1321N1 cells assessed as ATP induced calcium response by measuring ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50596624(CHEMBL5204261)
Affinity DataEC50:  8.97E+3nMAssay Description:Negative allosteric modulation activity at human P2X4 receptor expressed in human 1321N1 cells assessed as ATP induced calcium response by measuring ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50596624(CHEMBL5204261)
Affinity DataIC50:  2.52E+4nMAssay Description:Negative allosteric modulation activity at human P2X7 receptor expressed in human 1321N1 cells assessed as reduction in intracellular Ca2+ influx inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50596624(CHEMBL5204261)
Affinity DataIC50:  40nMAssay Description:Negative allosteric modulation activity at human P2X4 receptor expressed in human 1321N1 cells assessed as reduction in intracellular Ca2+ influx inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50596624(CHEMBL5204261)
Affinity DataEC50:  1.22E+4nMAssay Description:Negative allosteric modulation activity at human P2X4 receptor expressed in human 1321N1 cells assessed as ATP induced calcium response by measuring ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed