BDBM50598954 CHEMBL5187830
SMILES COC(=O)NCCCn1cc(CN(C2CC2)C(=O)[C@H]2CNCCO2)c2ccccc12
InChI Key InChIKey=NIPWZZBPFRFZBX-HXUWFJFHSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50598954
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human recombinant renin (67 to 406 residues) expressed in HEK293 cells using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp as fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of renin activity in human plasma by competitive radio immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Displacement of 125I-labeled angiotensin I from from human plasma renin by gamma counter based competitive radioimmunoassayMore data for this Ligand-Target Pair