BDBM50600302 CHEMBL5193437
SMILES COc1ccc(cc1)C1(CCCC1)C(=O)N1C[C@H](F)C[C@@H]1C(=O)Nc1cccc2[nH]ncc12
InChI Key InChIKey=FLUJAHQWJJQENP-VGOFRKELSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50600302
Affinity DataIC50: 460nMAssay Description:Inhibition of EP300 in human LK2 cells assessed as reduction in intracellular histone H3 acetylation at lysine 27 residue incubated for 3 hrs by chem...More data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Inhibition of N-terminal His tagged human EP300 (1159-1666 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H4 (1 to 25)-GSGSK p...More data for this Ligand-Target Pair