BDBM50600846 CHEMBL5170406

SMILES Cn1cc2c3cc(ccc3n(-c3ccc(cc3)C(F)(F)F)c2n1)C(O)=O

InChI Key InChIKey=HUSMWXZHQVTDRU-UHFFFAOYSA-N

Data  7 IC50  4 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50600846   

TargetTranscriptional enhancer factor TEF-1(Homo sapiens)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50600846(CHEMBL5170406)
Affinity DataKd:  120nMAssay Description:Binding affinity to human TEAD1 (209 to 426 residues) expressed in Escherichia coli BL21 Star (DE3) by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetTranscriptional enhancer factor TEF-4(Homo sapiens)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50600846(CHEMBL5170406)
Affinity DataKd:  4.60E+3nMAssay Description:Binding affinity to human TEAD2 (217 to 447 residues) expressed in Escherichia coli BL21 Star (DE3) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTranscriptional enhancer factor TEF-5(Homo sapiens)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50600846(CHEMBL5170406)
Affinity DataKd:  1.40E+3nMAssay Description:Binding affinity to human TEAD3 (216 to 435 residues) expressed in Escherichia coli BL21 Star (DE3) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTranscriptional enhancer factor TEF-3(Homo sapiens)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50600846(CHEMBL5170406)
Affinity DataKd:  5.40E+3nMAssay Description:Binding affinity to human TEAD4 (217 to 434 residues) expressed in Escherichia coli BL21 Star (DE3) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50600846(CHEMBL5170406)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50600846(CHEMBL5170406)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50600846(CHEMBL5170406)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50600846(CHEMBL5170406)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50600846(CHEMBL5170406)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50600846(CHEMBL5170406)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50600846(CHEMBL5170406)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2B6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed