BDBM50601138 CHEMBL5184056

SMILES Clc1ccc(C#N)c(n1)-n1ccc2ncncc12

InChI Key InChIKey=AFZXKZNWMHCMPD-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50601138   

TargetRibosomal protein S6 kinase alpha-4(Homo sapiens (Human))
Ucb

Curated by ChEMBL
LigandPNGBDBM50601138(CHEMBL5184056)
Affinity DataIC50:  20nMAssay Description:Inhibition of MSK2 (unknown origin) FAM-PSKPAATRKRRWSAPESR-NH2 as substrate preincubated for 1 hr followed by activation with ERK2 and substrate addi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Ucb

Curated by ChEMBL
LigandPNGBDBM50601138(CHEMBL5184056)
Affinity DataIC50:  13nMAssay Description:Inhibition of full-length N-terminal His-TEV-tagged inactive form of MSK1 (2 to 802 residues) (unknown origin) expressed in HEK293 cells using FAM-PS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB