BDBM50601160 CHEMBL5187801

SMILES Clc1cnc(Cl)nc1-n1ccc2ncccc12

InChI Key InChIKey=KBGCWMXCIHNWOI-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50601160   

TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Ucb

Curated by ChEMBL
LigandPNGBDBM50601160(CHEMBL5187801)
Affinity DataIC50:  200nMAssay Description:Inhibition of full-length N-terminal His-TEV-tagged inactive form of MSK1 (2 to 802 residues) (unknown origin) expressed in HEK293 cells using FAM-PS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Ucb

Curated by ChEMBL
LigandPNGBDBM50601160(CHEMBL5187801)
Affinity DataIC50:  200nMAssay Description:Inhibition of full-length N-terminal His-TEV-tagged inactive form of MSK1 (2 to 802 residues) (unknown origin) expressed in HEK293 cells using FAM-PS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Ucb

Curated by ChEMBL
LigandPNGBDBM50601160(CHEMBL5187801)
Affinity DataIC50:  2.51E+3nMAssay Description:Inhibition of full-length N-terminal His-TEV-tagged inactive form of MSK1 (2 to 802 residues) (unknown origin) expressed in HEK293 cells using FAM-PS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Ucb

Curated by ChEMBL
LigandPNGBDBM50601160(CHEMBL5187801)
Affinity DataIC50:  63nMAssay Description:Inhibition of full-length N-terminal His-TEV-tagged inactive form of MSK1 (2 to 802 residues) (unknown origin) expressed in HEK293 cells using FAM-PS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRibosomal protein S6 kinase alpha-4(Homo sapiens (Human))
Ucb

Curated by ChEMBL
LigandPNGBDBM50601160(CHEMBL5187801)
Affinity DataIC50:  794nMAssay Description:Inhibition of MSK2 (unknown origin) FAM-PSKPAATRKRRWSAPESR-NH2 as substrate preincubated for 1 hr followed by activation with ERK2 and substrate addi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Ucb

Curated by ChEMBL
LigandPNGBDBM50601160(CHEMBL5187801)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of N-terminal His-Smt-tagged MSK1 C-terminal kinase domain (414 to 738 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Ucb

Curated by ChEMBL
LigandPNGBDBM50601160(CHEMBL5187801)
Affinity DataIC50: <1.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human MSK1 (2 to end residues) expressed in baculovirus infected Sf21 insect cells using FAM-PSKPAAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Ucb

Curated by ChEMBL
LigandPNGBDBM50601160(CHEMBL5187801)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human MSK1 (2 to end residues) expressed in baculovirus infected Sf21 insect cells using FAM-PSKPAAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Ucb

Curated by ChEMBL
LigandPNGBDBM50601160(CHEMBL5187801)
Affinity DataIC50:  398nMAssay Description:Inhibition of N-terminal His-Smt-tagged MSK1 C-terminal kinase domain (414 to 738 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Ucb

Curated by ChEMBL
LigandPNGBDBM50601160(CHEMBL5187801)
Affinity DataIC50:  398nMAssay Description:Inhibition of N-terminal His-Smt-tagged MSK1 C-terminal kinase domain (414 to 738 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Ucb

Curated by ChEMBL
LigandPNGBDBM50601160(CHEMBL5187801)
Affinity DataIC50:  1.58E+4nMAssay Description:Inhibition of N-terminal His-Smt-tagged MSK1 C-terminal kinase domain (414 to 738 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Ucb

Curated by ChEMBL
LigandPNGBDBM50601160(CHEMBL5187801)
Affinity DataIC50:  126nMAssay Description:Inhibition of full-length N-terminal His-TEV-tagged inactive form of MSK1 (2 to 802 residues) (unknown origin) expressed in HEK293 cells using FAM-PS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed