BDBM50605281 CHEMBL5194957

SMILES Clc1ccc(N2N=C(CC2=O)C23CC4CC(CC(C4)C2)C3)c(Cl)c1

InChI Key InChIKey=XSJQXGATKBPUBO-UHFFFAOYSA-N

Data  1 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50605281   

TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50605281(CHEMBL5194957)
Affinity DataKd:  19nMAssay Description:Binding affinity towards His-tagged recombinant human PD-L1 measured by MicroScale Thermophoresis (MST) assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50605281(CHEMBL5194957)
Affinity DataKd:  177nMAssay Description:Binding affinity towards His-tagged recombinant human PD-L1 measured by Isothermal Titration Calorimetry (ITC) assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50605281(CHEMBL5194957)
Affinity DataIC50:  9nMAssay Description:Inhibition of human PD-1/PD-L1 interaction in CHO-K1 cells transfected with PD-1-YFP/SHP-2-CFP and measured by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50605281(CHEMBL5194957)
Affinity DataKd:  24nMAssay Description:Binding affinity towards His-tagged recombinant human PD-L1 measured by MST dimerization binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed