BDBM50605535 CHEMBL5198962
SMILES Fc1c(Cl)ccc(Cl)c1C(=O)c1c[nH]c(c1)C(=O)Nc1cnn(CC2CCNCC2)c1
InChI Key InChIKey=RMXRWGZHGVSUOH-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50605535
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
Newcastle University Centre For Cancer
Curated by ChEMBL
Newcastle University Centre For Cancer
Curated by ChEMBL
Affinity DataIC50: 671nMAssay Description:Inhibition of ERK5 phosphorylation in human HeLa cells incubated for 1 hr by Western blot densitometry analysisMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
Newcastle University Centre For Cancer
Curated by ChEMBL
Newcastle University Centre For Cancer
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of ERK5 (unknown origin) using K-5FAM-LVEPLTPSGEAPNQ-COOH as substrate incubated for 2 hrs in presence of ATP by IMAP-FP assayMore data for this Ligand-Target Pair