BDBM50605644 CHEMBL5209093

SMILES OC(=O)CNC(=O)c1nc(Br)c2cc(Oc3ccccc3)ccc2c1O

InChI Key InChIKey=MOOCHEISIIMJAU-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50605644   

TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Guangzhou Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50605644(CHEMBL5209093)
Affinity DataEC50:  15nMAssay Description:Agonist activity at wild type human TR alpha LBD expressed in Escherichia coli BL21 (DE3) assessed as induction of N-terminal biotinylated coactivato...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Guangzhou Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50605644(CHEMBL5209093)
Affinity DataIC50:  58nMAssay Description:Inhibition of PHD2 (unknown origin) incubated for 15 mins by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Guangzhou Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50605644(CHEMBL5209093)
Affinity DataEC50:  3.40nMAssay Description:Agonist activity at human TR beta LBD (202 to 461 residues) expressed in Escherichia coli BL21 (DE3) cells assessed as induction of N-terminal biotin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed