BDBM50607600 CHEMBL5220956

SMILES FC1(F)CC(C1)(C(=O)N1CCC[C@@H]1C(=O)Nc1ccc2[nH]ncc2n1)c1ccc(Cl)cc1

InChI Key InChIKey=ZEXRVLSADZXFLV-QGZVFWFLSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50607600   

TargetHistone acetyltransferase p300(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50607600(CHEMBL5220956)
Affinity DataIC50:  0.316nMAssay Description:Inhibition of full-length P300 (unknown origin) using ARTKQTARKSTGGKAPRKQLAGG-K(Biotin)-amide as substrate preincubated for 60 mins followed by subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCREB-binding protein/Histone acetyltransferase p300(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50607600(CHEMBL5220956)
Affinity DataEC50:  16nMAssay Description:Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50607600(CHEMBL5220956)
Affinity DataIC50:  0.631nMAssay Description:Inhibition of full-length P300 (1 to 2414 residues) (unknown origin) using ARTKQTARKSTGGKAPRKQLAGG-K(Biotin)-amide as substrate preincubated for 60 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed