BDBM50607601 CHEMBL5219667
SMILES F[C@@H]1C[C@@H](N(C1)C(=O)C1(CCC1)c1ccc(Cl)cc1)C(=O)Nc1ccc2[nH]ncc2n1
InChI Key InChIKey=OSDVXRQBLRRNJD-CRAIPNDOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50607601
TargetCREB-binding protein/Histone acetyltransferase p300(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 6.30nMAssay Description:Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of full-length P300 (unknown origin) using ARTKQTARKSTGGKAPRKQLAGG-K(Biotin)-amide as substrate preincubated for 60 mins followed by subst...More data for this Ligand-Target Pair