BDBM508829 US11071721, Example 73::US11607396, Example 73

SMILES FC[C@@H]1CC(F)(F)CN1C(=O)c1nc2[C@@H](F)C[C@@H](c3ccccc3)n2n1

InChI Key InChIKey=NVAOGSBYGQQIJC-AVGNSLFASA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 508829   

TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM508829(US11071721, Example 73 | US11607396, Example 73)
Affinity DataKi:  82nMAssay Description:The ability of the receptor interacting protein kinase (RIPK1) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) is monitored using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM508829(US11071721, Example 73 | US11607396, Example 73)
Affinity DataKi:  82nMAssay Description:The ability of the receptor interacting protein kinase (RIPK1) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) is monitored using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent