BDBM510980 1-(2,2-difluoroethyl)-6-(2- hydroxy-2- methylpropoxy)-N-[(4s)-6- ({5-carbamoyl-1-methyl- 1H-pyrazolo[3,4-b]pyridin- 6-yl}oxy)spiro[3.3]heptan- 2-yl]-1H-indazole-3- carboxamide::US11078197, Example 159::US11673886, Example 159
SMILES Cn1ncc2cc(C(N)=O)c(O[C@H]3C[C@@]4(C[C@@H](C4)NC(=O)c4nn(CC(F)F)c5cc(OCC(C)(C)O)ccc45)C3)nc12
InChI Key InChIKey=VRQTZJJHVKGEGX-ZVXFEBSPSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 510980
Affinity DataIC50: 1.10nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair