BDBM511057 US11078214, Compound 12

SMILES Cc1nc(N)nc2ccc(Nc3ccc(OC(F)(F)F)cc3)nc12

InChI Key InChIKey=ZSJZSDZJWHODCC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 511057   

TargetDihydrofolate reductase(Human pneumocystis pneumonia agent)
Duquesne University of The Holy Spirit

US Patent
LigandPNGBDBM511057(US11078214, Compound 12)
Affinity DataIC50:  4.13E+3nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University of The Holy Spirit

US Patent
LigandPNGBDBM511057(US11078214, Compound 12)
Affinity DataIC50:  194nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent