BDBM518020 8-[[1-(2,2-difluoroacetyl)azetidin-3-yl]oxy-4-[(2R)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2- hydroxy-propyl]-2,3-dihydro-1,4-benzoxazepin-5-one::US11111237, Example 161::US11725001, Example 161

SMILES O[C@H](CN1CCc2ccccc2C1)CN1CCOc2cc(OC3CN(C3)C(=O)C(F)F)ccc2C1=O

InChI Key InChIKey=RJBMCGQKXRBJML-LJQANCHMSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 518020   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM518020(8-[[1-(2,2-difluoroacetyl)azetidin-3-yl]oxy-4-[(2R...)
Affinity DataIC50:  50nMAssay Description:The histone H4 peptide was diluted with carbonate-bicarbonate buffer and prepared to 100 μg/mL, and then dispensed onto the plate per 100 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM518020(8-[[1-(2,2-difluoroacetyl)azetidin-3-yl]oxy-4-[(2R...)
Affinity DataIC50:  50nMAssay Description:Experimental procedure: The histone H4 peptide was diluted with carbonate-bicarbonate buffer and prepared to 100 μg/mL, and then dispensed onto ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent