BDBM518091 4-[(2R)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxy-propyl]-8-(3-hydroxybu-1-tynyl)- 2,3-dihydro-1,4-benzoxazepin-5-one::US11111237, Example 228::US11725001, Example 228

SMILES CC(O)C#Cc1ccc2c(OCCN(C[C@H](O)CN3CCc4ccccc4C3)C2=O)c1

InChI Key InChIKey=ZMZHQWVOASYZTH-LMNIDFBRSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 518091   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM518091(4-[(2R)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydr...)
Affinity DataIC50:  50nMAssay Description:The histone H4 peptide was diluted with carbonate-bicarbonate buffer and prepared to 100 μg/mL, and then dispensed onto the plate per 100 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM518091(4-[(2R)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydr...)
Affinity DataIC50:  50nMAssay Description:Experimental procedure: The histone H4 peptide was diluted with carbonate-bicarbonate buffer and prepared to 100 μg/mL, and then dispensed onto ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent