BDBM520046 (R)-methyl 4-(2-chloro-4-fluorophenyl)-6-(((S)-2-(4-(2-methyl-1H-imidazol-5-yl) phenyl)-3-oxohexahydroimidazo[1,5-a]pyrazin-7(1H)-yl)methyl)-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate::US11142527, Example 107

SMILES COC(=O)C1=C(CN2CCN3[C@H](CN(C3=O)c3ccc(cc3)-c3cnc(C)[nH]3)C2)NC(=N[C@H]1c1ccc(F)cc1Cl)c1nccs1

InChI Key

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 520046   

TargetLarge envelope protein(Hepatitis B virus)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM520046((R)-methyl 4-(2-chloro-4-fluorophenyl)-6-(((S)-2-(...)
Affinity DataEC50:  6.5nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent