BDBM522105 US11160797, Example 13

SMILES CCC(CC)Cn1cc(ccc1=O)-c1cncc(c1)-c1ccc2N(C)C(=O)Cc2c1

InChI Key InChIKey=CYGLZRHAOWDGHJ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 522105   

TargetActivin receptor type-1 [172-499](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM522105(US11160797, Example 13)
Affinity DataIC50:  680nMAssay Description:Example 53: The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 6 ul. Dose-response curves were g...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBone morphogenetic protein receptor type-1A [198-525](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM522105(US11160797, Example 13)
Affinity DataIC50:  8.50E+3nMAssay Description:Example 53: The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 6 ul. Dose-response curves were g...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetActivin receptor type-1 [172-499](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM522105(US11160797, Example 13)
Affinity DataIC50:  620nMAssay Description:Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBone morphogenetic protein receptor type-1B [168-495](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM522105(US11160797, Example 13)
Affinity DataIC50: >1.00E+4nMAssay Description:Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3 [166-493](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM522105(US11160797, Example 13)
Affinity DataIC50:  5.30E+3nMAssay Description:Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1 [162-503](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM522105(US11160797, Example 13)
Affinity DataIC50: >1.00E+4nMAssay Description:Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetActivin receptor type-1 [172-499,R206H](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM522105(US11160797, Example 13)
Affinity DataIC50:  570nMAssay Description:Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent