BDBM529481 2-(2-chloro-4-fluorophenoxy)-N-(3-sulfamoylphenyl)-6-(trifluoromethyl)benzamide ::US11203571, Compound 33

SMILES NS(=O)(=O)c1cccc(NC(=O)c2c(Oc3ccc(F)cc3Cl)cccc2C(F)(F)F)c1

InChI Key InChIKey=GLYONJOHRRWFQM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 529481   

TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM529481(2-(2-chloro-4-fluorophenoxy)-N-(3-sulfamoylphenyl)...)
Affinity DataIC50:  5nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent