BDBM532293 N-(3,5-diethyl-1H-pyrazol-4-yl)-2-[2-(difluoromethoxy)-4-(4-methylpiperazin-1-yl)anilino]-5,6-dihydropyrimido[4,5-e]indolizine-7-carboxamide::US11208696, Example 12::WITJ453B

SMILES CCc1n[nH]c(CC)c1NC(=O)c1ccn-2c1CCc1cnc(Nc3ccc(cc3OC(F)F)N3CCN(C)CC3)nc-21

InChI Key InChIKey=CMSARXIYXRBTSN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 532293   

TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Netherlands Translational Research Center

US Patent
LigandPNGBDBM532293(N-(3,5-diethyl-1H-pyrazol-4-yl)-2-[2-(difluorometh...)
Affinity DataIC50:  0.970nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP®...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent