BDBM532296 N-[1-(2-m ethoxy yl-3,5-dimethyl-pyrazol-4-yl]-2-(2-methoxy-4-piperazin-1-yl-anilino)-5,6-dihydropyrimido[4,5-e]indolizine-7-carboxamide::US11208696, Example 15::WITJ349B

SMILES COCCn1nc(C)c(NC(=O)c2ccn-3c2CCc2cnc(Nc4ccc(cc4OC)N4CCNCC4)nc-32)c1C

InChI Key InChIKey=SFSWXUYFZCJIHP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 532296   

TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Netherlands Translational Research Center

US Patent
LigandPNGBDBM532296(N-[1-(2-m ethoxy yl-3,5-dimethyl-pyrazol-4-yl]-2-(...)
Affinity DataIC50:  1.10nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP®...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent