BDBM532299 N-(2,6-dimethylphenyl)-2-[2-methoxy-4-[(1-methyl-4-piperidyloxy]anilino]pyrimido[4,5-e]indolizine-7-carboxamide::US11208696, Example 18::WITJ490B

SMILES COc1cc(OC2CCN(C)CC2)ccc1Nc1ncc2ccc3c(ccn3c2n1)C(=O)Nc1c(C)cccc1C

InChI Key InChIKey=VIBCASKLAZRVHT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 532299   

TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Netherlands Translational Research Center

US Patent
LigandPNGBDBM532299(N-(2,6-dimethylphenyl)-2-[2-methoxy-4-[(1-methyl-4...)
Affinity DataIC50:  1.40nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP®...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent