BDBM5329 3-(5-{2-[(2-methoxyethyl)(methyl)amino]ethoxy}-1H-indol-2-yl)-1,2-dihydroquinolin-2-one::indolyl quinolinone deriv. 4

SMILES COCCN(C)CCOc1ccc2[nH]c(cc2c1)-c1cc2ccccc2[nH]c1=O

InChI Key InChIKey=IVKQYQMLUAZKPB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 5329   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM5329(3-(5-{2-[(2-methoxyethyl)(methyl)amino]ethoxy}-1H-...)
Affinity DataIC50:  7nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed