BDBM534380 5-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl)-N-(2,2-difluoro-3-(4-fluorophenyl)-3-hydroxypropyl)-3,4-difluoro-2 -methylbenzamide enantiomer 2::WO2022086828, Example 107
SMILES Cc1c(F)c(F)c(cc1C(=O)NCC(F)(F)[C@H](O)c1ccc(F)cc1)-c1ccn2nc(N)nc2c1
InChI Key InChIKey=UYFPVIQBUYGAII-HXUWFJFHSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 534380
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Bristol-Myers Squibb
WIPO
Bristol-Myers Squibb
WIPO
Affinity DataIC50: >1.50E+4nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 40 nM probe and 1 nM GST-tagged PIK3C5 in complex with PIK3R1 (Invitrogen #...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb
WIPO
Bristol-Myers Squibb
WIPO
Affinity DataIC50: 0.400nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair