BDBM536813 5-(8-(5-acetyl-1-(tetrahydro-2H-pyran-4-yl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl)-4-fluoroisoquinolin-3-yl)-N-methylpicolinamide::US11247989, Example 24

SMILES CNC(=O)c1ccc(cn1)-c1ncc2c(cccc2c1F)-c1nn(C2CCOCC2)c2CCN(Cc12)C(C)=O

InChI Key InChIKey=TUVOZXGYQPNWGN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 536813   

TargetCREB-binding protein(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM536813(5-(8-(5-acetyl-1-(tetrahydro-2H-pyran-4-yl)-4,5,6,...)
Affinity DataIC50:  2.05nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent