BDBM5410 4-(2-(4-(3-phenylpyrazolo[1,5- a]pyrimidin-6-yl)phenoxy)ethyl)morpholine::4-[2-(4-{3-phenylpyrazolo[1,5-a]pyrimidin-6-yl}phenoxy)ethyl]morpholine::US9040694, 4::pyrazolo[1,5-a]pyrimidine 4b

SMILES C(CN1CCOCC1)Oc1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccccc1

InChI Key InChIKey=SKZQZGSPYYHTQG-UHFFFAOYSA-N

Data  9 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 5410   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM5410(4-(2-(4-(3-phenylpyrazolo[1,5- a]pyrimidin-6-yl)ph...)
Affinity DataIC50:  9nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed