BDBM543851 2-{4-[(1R)-1-[(4-chloro-1,6-dimethyl-1H-indol-2- yl)formamido]ethyl]benzenesulfinyl}acetic acid::US11304929, Example 12-004

SMILES C[C@@H](NC(=O)c1cc2c(Cl)cc(C)cc2n1C)c1ccc(cc1)S(=O)CC(O)=O

InChI Key InChIKey=VBQXPKOVIPZVMB-RNHBAAACSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 543851   

TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM543851(2-{4-[(1R)-1-[(4-chloro-1,6-dimethyl-1H-indol-2- y...)
Affinity DataIC50:  18nMAssay Description:Compounds are dispensed onto assay plates (black, low volume, flat bottom 384 well, Corning) using an Access Labcyte Workstation with the Labcyte Ech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM543851(2-{4-[(1R)-1-[(4-chloro-1,6-dimethyl-1H-indol-2- y...)
Affinity DataIC50:  11nMAssay Description:Compounds are dispensed onto assay plates (black, low volume, flat bottom 384 well, Corning) using an Access Labcyte Workstation with the Labcyte Ech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent