BDBM5485 6-(cyclohexylmethoxy)-9H-purin-2-amine::CHEMBL269881::NU2058

SMILES Nc1nc(OCC2CCCCC2)c2[nH]cnc2n1

InChI Key InChIKey=MWGXGTJJAOZBNW-UHFFFAOYSA-N

Data  3 KI  7 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5485   

TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
University of Newcastle

LigandPNGBDBM5485(6-(cyclohexylmethoxy)-9H-purin-2-amine | CHEMBL269...)
Affinity DataIC50:  7.00E+3nMpH: 7.5 T: 2°CAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2 [171-432]/Cyclin-dependent kinase 2(Homo sapiens (Human))
University of Newcastle

LigandPNGBDBM5485(6-(cyclohexylmethoxy)-9H-purin-2-amine | CHEMBL269...)
Affinity DataIC50:  1.70E+4nMpH: 7.5 T: 2°CAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair