BDBM550684 8-methyl-6-[(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-2H-spiro[imidazo[1,5-a]pyridine-3,3′-thietane]-1,5-dione::US11311520, Example 178

SMILES Cc1cc(Nc2ncnc3[nH]ccc23)c(=O)n2c1C(=O)NC21CSC1

InChI Key InChIKey=QEYRMIPSUBGLHN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 550684   

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM550684(8-methyl-6-[(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino...)
Affinity DataIC50:  1.10nMAssay Description:MKNK1-inhibitory activity at high ATP of compounds of the present invention after their preincubation with MKNK1 was quantified employing the TR-FRET...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent