BDBM554532 US11337973, Example 37::[(5-Chloropyridin-3-yl)methyl]-7-{[(1 RS)-2,2-difluorocyclopropyl]methyl}-5-{[(3S)-3-fluoropyrrolidin-1-yl]carbonyl}-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazin-3(2H)-one (Isomer 1)

SMILES F[C@H]1CCN(C1)C(=O)C1CN(CC2CC2(F)F)Cc2nn(Cc3cncc(Cl)c3)c(=O)n12

InChI Key InChIKey=XCZXTWWCOBYBCZ-SIWZUTFBSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 554532   

TargetProlyl endopeptidase(Homo sapiens (Human))
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US Patent
LigandPNGBDBM554532(US11337973, Example 37 | [(5-Chloropyridin-3-yl)me...)
Affinity DataIC50:  47nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent