BDBM5559 (6-Cyclohexylmethoxy-9H-purin-2-yl)thiophen-2-ylmethylamine::6-(cyclohexylmethoxy)-N-(thiophen-2-ylmethyl)-9H-purin-2-amine::O6-Cyclohexylmethylguanine deriv. 43

SMILES C(Nc1nc(OCC2CCCCC2)c2[nH]cnc2n1)c1cccs1

InChI Key InChIKey=FTBFCDGGIMYWCL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5559   

TargetCyclin-A2 [171-432]/Cyclin-dependent kinase 2(Homo sapiens (Human))
University of Newcastle

LigandPNGBDBM5559((6-Cyclohexylmethoxy-9H-purin-2-yl)thiophen-2-ylme...)
Affinity DataIC50:  1.70E+3nMAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
University of Newcastle

LigandPNGBDBM5559((6-Cyclohexylmethoxy-9H-purin-2-yl)thiophen-2-ylme...)
Affinity DataIC50:  700nMAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed