BDBM558848 US11370770, Compound 6a
SMILES OC(=O)c1cccc(c1)-c1n[nH]c2ccccc12
InChI Key InChIKey=FEOVMUZHGLJSAV-UHFFFAOYSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 558848
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: 640nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: 180nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: 460nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Affinity DataIC50: 7.20E+3nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Affinity DataIC50: 8.30E+3nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+4nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Affinity DataIC50: >2.70E+4nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Affinity DataIC50: >2.70E+4nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair