BDBM559092 US11370774, Compound 218f::US11708347, Compound 218f

SMILES Cn1ccc2cc(COc3ccccc3CC(O)=O)cc(-c3cccc(CN)c3)c12

InChI Key InChIKey=MASUUZIXWKCABO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 559092   

TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

US Patent
LigandPNGBDBM559092(US11370774, Compound 218f | US11708347, Compound 2...)
Affinity DataIC50: <1.00E+3nMAssay Description:An established esterolytic assay for the measurement of Factor D activity and inhibition of Factor D activity was used. For this assay Z-Lys-SBzl, 1....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

US Patent
LigandPNGBDBM559092(US11370774, Compound 218f | US11708347, Compound 2...)
Affinity DataIC50: >1.00E+4nMAssay Description:An established esterolytic assay for the measurement of Factor D activity and inhibition of Factor D activity was used (Kam, C. M.; McRae, B. J.; Har...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent