BDBM559432 US11370774, Compound 533c::US11708347, Compound 533c

SMILES NCc1nccc(c1F)-c1cc(COc2ccccc2CC(O)=O)cc2n(ccc12)C(F)(F)F

InChI Key InChIKey=CMKZJSZDGAXNRF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 559432   

TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

US Patent
LigandPNGBDBM559432(US11370774, Compound 533c | US11708347, Compound 5...)
Affinity DataIC50: <1.00E+4nMAssay Description:An established esterolytic assay for the measurement of Factor D activity and inhibition of Factor D activity was used. For this assay Z-Lys-SBzl, 1....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

US Patent
LigandPNGBDBM559432(US11370774, Compound 533c | US11708347, Compound 5...)
Affinity DataIC50: <1.00E+3nMAssay Description:An established esterolytic assay for the measurement of Factor D activity and inhibition of Factor D activity was used (Kam, C. M.; McRae, B. J.; Har...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent