BDBM563099 (3S)-N-{2-fluoro-4-melhyl-5-[2-(1- methylpyrazol-4-yl)-6-(morpholin-4- yl)pyridin-4-yl]phenyl}-3-(2,2,2- trifluoroethyl)pyrrolidine-1-carboxamide::US11407737, Example 74

SMILES Cc1cc(F)c(NC(=O)N2CC[C@@H](CC(F)(F)F)C2)cc1-c1cc(nc(c1)-c1cnn(C)c1)N1CCOCC1

InChI Key InChIKey=NUUFJKICXAGCSC-SFHVURJKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 563099   

TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Kinnate Biopharma

US Patent
LigandPNGBDBM563099((3S)-N-{2-fluoro-4-melhyl-5-[2-(1- methylpyrazol-4...)
Affinity DataIC50: <1nMAssay Description:Assay platform was used to measure kinase/inhibitor interactions as described previously (Anastassiadis et al., 2011). In brief, for each reaction, k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent