BDBM563612 Cyclopropanecarboxylic acid [4- (2-{2-[3-(5-tert-butyl-2-p-tolyl- 2H-pyrazol-3-yl)-ureido]-thiazol- 5-yl}ethyl)-pyridin-2-yl]-amide::US11407771, Compound 331

SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ncc(CCc2ccnc(NC(=O)C3CC3)c2)s1)C(C)(C)C

InChI Key InChIKey=JQZOHNXEVNSVST-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 563612   

TargetMitogen-activated protein kinase 13(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM563612(Cyclopropanecarboxylic acid [4- (2-{2-[3-(5-tert-b...)
Affinity DataIC50: <250nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM563612(Cyclopropanecarboxylic acid [4- (2-{2-[3-(5-tert-b...)
Affinity DataIC50:  202nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 13(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM563612(Cyclopropanecarboxylic acid [4- (2-{2-[3-(5-tert-b...)
Affinity DataIC50:  11nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM563612(Cyclopropanecarboxylic acid [4- (2-{2-[3-(5-tert-b...)
Affinity DataIC50:  202nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent