BDBM563618 N-[4-[2-[2-[[5-tert-butyl-2-(p- tolyl)pyrazol-3- yl]carbamoylamino]thiazol-5- yl]ethyl]-2-pyridyl]-3-methoxy- propanamide::US11407771, Compound 283

SMILES COCCC(=O)Nc1cc(CCc2cnc(NC(=O)Nc3cc(nn3-c3ccc(C)cc3)C(C)(C)C)s2)ccn1

InChI Key InChIKey=ZMEOOGRKZQQMAP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 563618   

TargetMitogen-activated protein kinase 13(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM563618(N-[4-[2-[2-[[5-tert-butyl-2-(p- tolyl)pyrazol-3- y...)
Affinity DataIC50: <250nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM563618(N-[4-[2-[2-[[5-tert-butyl-2-(p- tolyl)pyrazol-3- y...)
Affinity DataIC50:  139nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 13(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM563618(N-[4-[2-[2-[[5-tert-butyl-2-(p- tolyl)pyrazol-3- y...)
Affinity DataIC50:  8nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM563618(N-[4-[2-[2-[[5-tert-butyl-2-(p- tolyl)pyrazol-3- y...)
Affinity DataIC50:  139nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent