BDBM574745 US11459315, Example 1 (isomer 1)

SMILES CSc1cc(C)[nH]c(=O)c1CNC(=O)c1c(C)n([C@H](C)[C@@H]2CC[C@@H](CC2)NC2(C)COC2)c2ccccc12

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 574745   

TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM574745(US11459315, Example 1 (isomer 1))
Affinity DataIC50:  0.5nMAssay Description:Compound potencies were assessed through incorporation of 3H-SAM into a biotinylated H3 peptide. Specifically, 30 pM PRC2 containing wt EZH2 (pentame...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent