BDBM589231 US11555009, Compound 5

SMILES OC(=O)c1ccccc1Nc1c(Cl)cc(cc1Cl)-c1ccncc1

InChI Key InChIKey=GSNZPZDSMBVGPU-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 589231   

TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM589231(US11555009, Compound 5)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of N-terminal His-tagged human FTO expressed in Escherichia coli BL21(DE3) by PAGE based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM589231(US11555009, Compound 5)
Affinity DataIC50: <5.00E+3nMAssay Description:The present invention provides a novel class of demethylase FTO inhibitors which inhibit FTO protein activity at very low concentration (typically IC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB