BDBM59225 Boronic acid, cis-6::Boronic acid, trans-6

SMILES COc1cc(C=Cc2ccc(OC)c(c2)B(O)O)cc(OC)c1OC

InChI Key InChIKey=QRZLVZGNSKRASS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 59225   

TargetTubulin polymerization-promoting protein(Homo sapiens (Human))
University of Virginia

LigandPNGBDBM59225(Boronic acid, cis-6 | Boronic acid, trans-6)
Affinity DataIC50:  1.50E+3nMAssay Description:Tubulin polymerization was followed turbidimetrically at 350nm in Beckman model DU-7400 and DU-7500 spectrophotometers equipped with electric tempera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin polymerization-promoting protein(Homo sapiens (Human))
University of Virginia

LigandPNGBDBM59225(Boronic acid, cis-6 | Boronic acid, trans-6)
Affinity DataIC50:  470nMAssay Description:IC50 values for inhibition of cell growth using MCF-7 cell line were obtained by measuring the amount of total cell protein with the sulforhodamine B...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin polymerization-promoting protein(Homo sapiens (Human))
University of Virginia

LigandPNGBDBM59225(Boronic acid, cis-6 | Boronic acid, trans-6)
Affinity DataIC50:  17nMAssay Description:IC50 values for inhibition of cell growth using MCF-7 cell line were obtained by measuring the amount of total cell protein with the sulforhodamine B...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin polymerization-promoting protein(Homo sapiens (Human))
University of Virginia

LigandPNGBDBM59225(Boronic acid, cis-6 | Boronic acid, trans-6)
Affinity DataIC50:  7.80E+3nMAssay Description:Tubulin polymerization was followed turbidimetrically at 350nm in Beckman model DU-7400 and DU-7500 spectrophotometers equipped with electric tempera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed