BDBM597781 (R)—N-(5-Cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-6-((N,1-dimethylpyrrolidin-2-carboxamido)methyl)-7-formyl-3,4-dihydro-1,8-naphthyridin-1(2H)-carboxamide::US11608332, Example 9

SMILES COCCNc1cc(NC(=O)N2CCCc3cc(CN(C)C(=O)[C@H]4CCCN4C)c(C=O)nc23)ncc1C#N

InChI Key InChIKey=UNOCIYDUNQBWEY-HSZRJFAPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 597781   

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM597781((R)—N-(5-Cyano-4-((2-methoxyethyl)amino)pyrid...)
Affinity DataIC50: >1.00E+4nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR1 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM597781((R)—N-(5-Cyano-4-((2-methoxyethyl)amino)pyrid...)
Affinity DataIC50:  0.740nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent